Francisca Mulero⁽¹⁾, J.A. Ruiz-Ros⁽²⁾, F. Martinez-Corbalan⁽³⁾, F. Picó⁽⁴⁾, J.A. Nuño de la Rosa^{(5)
(1)(2)(5)}Hospital Universitario Virgen de la Arrixaca - San Miguel de Salinas. Spain
⁽³⁾⁽⁴⁾Servicio de Medicina Nuclear. Hospital Universitario Virgen de la Arrixaca - Murcia. Spain

	[Genetics & Bioinformatics]	[Radiology & Nuclear Medicine]

RESULTS

21 out of 24 Syndrome X patients showed a normal pattern in the slices studies and polar maps; 3 patients showed a slight defects. Interestingly, those 21 patients with normal slices studies and polar maps also showed abnormal washouts. The patients that showed normal washouts, also had normal slices studies and polar maps.

Figure 1 Figure 2

PATIENTS WITH SYNDROME X AND CONTROLS DATA

* Statistical analysis (t de Student ). Syndrome X versus controls

THALLIUM SCANS	Syndrome X	Controls	p Value*
Mean stress counts	83.72 ± 4	111.99	< 0.05
Mean redist counts	86.22 ± 4	108.13	< 0.05
Washout	-3.11 ± 2.27	3.44	< 0.05

 

CLINICAL DATA	Ergometric characteristics
ST depression (mm)	1.9 ± 0.6
HR at max. ST depression	135.2 ± 19.1
Time ST depression	278.5 ± 182.2
HR at 1 mm ST depression	124.8 ± 19.1
Time 1 mm ST depression	261.2 ± 205.4
HR x SBP	26641 ± 4017
METZs	7.2 ± 2.9
Post-Exercise ST Recuperation time	160.0 ± 153.7
SBP (mm Hg)	192.1 ± 21.7
DBP (mm Hg)	89.6 ± 11.2

 

( DBP: Diastolic blood pressure; HR: Heart rate b/min; METZs: Metabolic equivalents;

SBP: Systolic blood pressure; Time: seconds ).

Syndrome X patients showed a significant reduction in Thallium 201 uptake at periods of peak exercise compared to the uptake shown by control subjects (83.72 vs 111.99; p < 0.05). Redistribution results show that Syndrome X patients have a higher Tallium uptake in resting periods than after exercise, whereas control individuals show lower values at rest than after excercise (86.22 patients, vs 108.13 controls; p < 0.05). Washout values are clearly reduced in syndrome X patients as compared to normal subjects (-3.10 vs 3.44; p < 0.05).

In control subjects, Thallium uptake at rest was reduced a 3,57 % as compared to uptake during exercise. However, Syndrome X patients showed an increase of 3,01% in Thallium uptake as compared to uptake during exercise.

Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [FIGURES] [DISCUSSION] [CONCLUSION] [Discussion Board]

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	[Genetics & Bioinformatics]	[Radiology & Nuclear Medicine]

Francisca Mulero, J.A. Ruiz-Ros, F. Martinez-Corbalan, F. Picó, J.A. Nuño de la Rosa
Copyright © 1999-2000. All rights reserved.

Last update: 16/01/00