Francisca Mulero⁽¹⁾, J.A. Ruiz-Ros⁽²⁾, F. Martinez-Corbalan⁽³⁾, F. Picó⁽⁴⁾, J.A. Nuño de la Rosa^{(5)
(1)(2)(5)}Hospital Universitario Virgen de la Arrixaca - San Miguel de Salinas. Spain
⁽³⁾⁽⁴⁾Servicio de Medicina Nuclear. Hospital Universitario Virgen de la Arrixaca - Murcia. Spain

	[Genetics & Bioinformatics]	[Radiology & Nuclear Medicine]

DISCUSSION

It has been proposed that a vasodilatation abnormality in the microvasculature is the cause of the reduction in coronary blood flow reserve shown by Syndrome X patients. This defect would result in a reversible perfusion abnormality that is clearly detectable using conventional scintigraphic analysis. Small or patched defects, however, may not always be detected by myocardial perfusion scintigraphy due to the limited spatial resolution of the technique, resulting in normal-appearing scintigraphic images.

The increase in Thallium uptake was in agreement with previous findings using PET. In these PET studies, Syndrome X patients showed an increase of perfusion at rest which conditions a diminution of coronary flow reserve and a reduction of the maximum perfusion at rest .

Apart from having a clear reduction in Thallium uptake, all Syndrome X patients included in this study showed a reduced washout value. In cases, washout values were negative, suggesting a reduction in coronary reserve flow in these patients.

Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [FIGURES] [DISCUSSION] [CONCLUSION] [Discussion Board]

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	[Genetics & Bioinformatics]	[Radiology & Nuclear Medicine]

Francisca Mulero, J.A. Ruiz-Ros, F. Martinez-Corbalan, F. Picó, J.A. Nuño de la Rosa
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Last update: 16/01/00