Alberto Pizarro Gallardo^(1)
(1)Facultad de Medicina U.A.N. - Tepic. Mexico

	[Obstetrics & Gynecology]
		[Oncology]	[Pathology]

RESULTS

All the patients were postmenopausal, they had irregular vaginal bleeding. Uterine enlargement was found in five patients and a mass was noted protruding from the endocervical canal in two; and never had been receiving strogen a radiation therapy. The patients were nuliparous and multiparous.

Light microscopy.

The AMU were composed of a mixture of histologically benign glands within a sarcomatous stroma. The most of the glands resembled endocervical epithelium or early prolifferative endometrium. (Fig1)

The stroma was hypercellular and composed of interwoven bundles of oval to spindle cells with hyperchromatic, often bizarre nuclei and prominent nucleoli. (fig2) Mitotic figures were atipical between 10 to 32 10 high power field (400x)

Electron microsocopy.

A. Epithelial cells. (24 cells)

The epithelium lining the gland was flat to cuboidal, with few foci of cellular stratification and minimal nuclear plemorphism. Many of the lining cells had a clear cytoplasm with an eccentrically nucleus suggestive of secretory activity. (Fig 3) Mitoses were not seen. The cells with abundant glycogen. The gland cells with microvilli in 92.3 %. The nuclei are fusiform, irregular and oval. In cytoplasm there are abundant RER in 95.2 %, golgi apparatus in 41 % the index nucleus-cytoplasm was 0.52, Cilia 40 % basal lamina in all cases. (Fig 4)

B. Mesenchymal cells. (30 cells)

The cells were moderately pleomorphic and spindle shaped separated by bundles of irregularly arrenged collagen. (Fig6) The cells was fusiform irregular and oval nuclei and prominent often multiple, nucleoli,(Fig5) index nuclei-cytoplasm means 0.58. No mitochondria means 8.6, rer means 7.2 and Golgi apparatus 6% Cilia and microvilli and basal lamina were absent.

Our identified 9 immature cells and 21 mature cells.

Six patient had homologous element and one heterologous element.

There was not transition between epithelium and stroma were observed. And there was not squamous metaplasia.

Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [DISCUSSION] [CONCLUSIONS] [BIBLIOGRAPHY] [Discussion Board]

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	[Obstetrics & Gynecology]
		[Oncology]	[Pathology]

Alberto Pizarro Gallardo
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Last update: 8/01/00