Peter Massanyi⁽¹⁾, Laszlo Bardos⁽²⁾, Robert Toman⁽³⁾, Svatoslav Hluchy⁽⁴⁾, Jaroslav Kovacik⁽⁵⁾, Norbert Lukac^{(6)
(1)(3)(4)(6)}Slovak Agricultural University - Nitra. Slovakia
⁽²⁾University of Agricultural Sciences - Godollo. Hungary
⁽⁵⁾Slovak University of Agriculture - Nitra. Slovakia

Contact address:

Peter Massanyi Slovak Agricultural University Tr. A. Hlinku 2 Nitra 94976 Slovakia massanyi@uniag.sk

	[Toxicology]	[Reproduction Sciences]

ABSTRACT

Cadmium was administered to 22 adult ICR mice i.p. in two single doses (0.25 and 0.5 mg CdCl2 per kg of b.w.). After 48 hours concentrations of cadmium in kidneys, liver, spleen, muscle (m. quadriceps femoris), ovaries and testes and the concentration of retinyl palmitate, retinol and ß-carotene in kidney, liver and testes were determined. Significantly higher cadmium concentration was found in liver, kidney and ovary in both experimental groups in comparison with the control group (P<0.001). In muscle, spleen and testis the cadmium level was higher, however not significantly. No significant differences in the concentration of retinyl palmitate, retinol and ß-carotene in liver were found. Concentration of ß-carotene in kidney and testis was significantly decreased in both groups administered with cadmium (P<0.001). Concentration of retinyl palmitate was significantly lower in testis in the group with higher cadmium level (P<0.001) and the concentration of retinol significantly decreased in kidney and testis of mice after an administration of 0.5 mg CdCl2/kg b.w.

---

Keywords: cadmium - accumulation - retinol palmitate - beta-carotene - retinol -

---

Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [DISCUSSION] [BIBLIOGRAPHY] [Discussion Board]

---

	[Toxicology]	[Reproduction Sciences]

Peter Massanyi, Laszlo Bardos, Robert Toman, Svatoslav Hluchy, Jaroslav Kovacik, Norbert Lukac
Copyright © 1999-2000. All rights reserved.

Last update: 10/01/00