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6th Internet World Congress for Biomedical Sciences

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EPITHELIAL SKIN CANCER IN HEAD AND NECK

Olatz Alcelay(1), Alejandro Nogueira(2), MŞ Jesús Martínez González(3), Teresa Pérez (4), Angel Perez Arias(5), Francisco Iglesias(6)
(1)(2)(3)(4)(5)(6)Hospital central de Asturias - Oviedo. Spain

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [IMAGES-2] [DISCUSSION] [CONCLUSIONS] [BIBLIOGRAPHY] [Discussion Board]
ABSTRACT Previous: RECONSTRUCTIVE MANAGEMENT OF MALIGNANT LIP TUMOURS
[Oral & Maxilofacial Surgery]
Previous: RECONSTRUCTIVE MANAGEMENT OF MALIGNANT LIP TUMOURS MATERIAL & METHODS
[Plastic Surgery]
Next: ESTERNUM OSTEOMIELITYS: RIB ALLOGRAFT AND HEMITURNOVER AND ADVANCEMENT PECTORALIS MAJOR FLAPS

INTRODUCTION Top Page

Epithelial skin cancer is the most frequent malignant tumour. They come from the epidermis and the epithelial structures, there are three main types: basal cell (the most prevalent), squamous cell and melanoma. They have a high rate of curation with early and suitable treatment. Certain skin carcinogens play an important part of development of precancerous and cancerous growth: UV-radiation, chemical carcinogens, ionising radiation and hereditary factors (1).

MATERIAL & METHODS Top Page

We have reviewed 115 patients (129 tumours) operated over 1-year-period with clinic diagnosis of epidermic malignant lesion in head and neck, bigger than 1 cm with histologic confirmation, operated under general anaesthesia.,,..

RESULTS Top Page

There is no sex predominance, the mean age of appearance are 74 years (graphic1), and some risk factors have been found: UV-radiation 35%, previous carcinoma 15% (graphic 2). Most common localised site are fronto-temporal 20%, nasal 19% and check 18% areas (graphic 3). 15% of patients presented more than one lesion at different areas. All are primary tumours presented over two-years period (graphic 4) and only 2% presented palpable lymph nodes at the moment at diagnosis.

The first surgery is made over 1 month after the diagnosis and some local structures were affected: bone, cartilage, muscle nerves (graphic 5). The surgery includes wide excision with one cm of margin and reconstructive procedure depending the size of the tumour, defect andfacial area (graphic 6) Loco-regional skins flaps are mainly used at lip, nasal and orbital area, skin grafts at fronto-temporal and scalp areas. Only 4% werw treated with radiotherapy after surgery.

The recurrence rate is 16,27% mainly at nasal area over 1 year after surgery (graphic7). The treatment consisted on wide excision, lymph node dissection and reconstruction of the area using mainly loco-regional or free flaps, 29% of the recurrences received radiation postsurgery.graphic7,graphic7,graphic7.

The most common histologic lesion found was basal cell carcinoma localised at nasal and orbital region (graphic 8, 9). The squamous cells were the most recurrent mainly at nasal area (graphic 10).

45% of patients have no sequels, 35% have any aesthetics ones and 3% were exitus.

DISCUSSION Top Page

The results reveal that the original tumour size, the location, and the histology are relationated with the recurrence rate.

Aggresive surgical treatment is needed to control the disease. Radiotherapy could be effective intreating on older individual with large tumour in whom extensive resection is unacceptable or where the goal is palliation (2,3).

CONCLUSIONS Top Page

The intermittent or continued exposition to UV- radiation increases the risk to present an epithelial skin cancer at sun exposed body areas. The basal cell carcinoma is the most common lesion, at people > 60 years odl. There is no sex predominance. The early diagnosis improves prognosis and decreases the morby-mortality rate with a suitable treatment. Excisional biopsy is the best technique to histopathologic diagnosis. Loco-regional flaps are the reconstructive procedure with better functional and aesthetic outcome. The recurrence is most frequent at unresectable lesion and histopathology aggressive tumours.

BIBLIOGRAPHY Top Page

  1. Friedman, Rigel, Koft et al. Cancer of skin. Philadelphia: Sanders, 1991
  2. Preston DS, Stern RS. Nomelanoma cancer of skin. N. Engl. J. Med.327: 1649, 1992.
  3. American Cancer Society, Cancer facts and figures. Georgia. ACS Publication.1992


Discussion Board
Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [IMAGES-2] [DISCUSSION] [CONCLUSIONS] [BIBLIOGRAPHY] [Discussion Board]

ABSTRACT Previous: RECONSTRUCTIVE MANAGEMENT OF MALIGNANT LIP TUMOURS
[Oral & Maxilofacial Surgery]
Previous: RECONSTRUCTIVE MANAGEMENT OF MALIGNANT LIP TUMOURS MATERIAL & METHODS
[Plastic Surgery]
Next: ESTERNUM OSTEOMIELITYS: RIB ALLOGRAFT AND HEMITURNOVER AND ADVANCEMENT PECTORALIS MAJOR FLAPS
Olatz Alcelay, Alejandro Nogueira, MŞ Jesús Martínez González, Teresa Pérez , Angel Perez Arias, Francisco Iglesias
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