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6th Internet World Congress for Biomedical Sciences

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ADP-RIBOSYLATION OF FILAMENTOUS ACTIN INDUCES ITS DEPOLYMERIZATION - THE ROLE OF ADP-RIBOSYLATION IN CYTOSKELETAL REORGANIZATION

Masaharu Terashima(1), Makoto Shimoyama(2), Mikako Tsuchiya(3)
(1)(2)(3)Department of Biochemistry. Shimane Medical University - Izumo. Japan

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS AND DISCUSSION] [FIGURES] [ACKNOWLEDGEMENTS] [REFERENCES] [Discussion Board]
ACKNOWLEDGEMENTS Previous: Testosterone modifies arylamidase activities in serum and different tissues of mice: an in vivo study. Previous: Intrinsic Membrane Properties and Synaptic Inputs Regulating The Firing Activity of the Dopamine Neurons. ABSTRACT
[Biochemistry]
Next: An extractable phosphatase inhibitor is present in the CSF of subarachnoid hemorrhage patients with vasospasm 		[Cell Biology & Cytology]
Next: Upregulation of phase II enzymes decreases the oxidative stress induced cell death in astrocytes.

REFERENCES

  1. Zolkiewska A, Okazaki IJ and Moss J (1994) Vertebrate mono-ADP-ribosyltransferase. Mol Cell Biochem 138:107-112.
  2. Mishima K, Terashima M, Obara S, Yamada K, Imai K and Shimoyama M (1991) Arginine-specific ADP-ribosyltransferase and its acceptor protein p33 in chicken polymorphonuclear cells: co-localization in the cell granules, partial characterization, and in situ mono(ADP-ribosyl)ation. J Biochem 110:388-394.
  3. Terashima M, Mishima K, Yamada K, Tsuchiya M, Wakutani T and Shimoyama M (1992) ADP-ribosylation of actins by arginine-specific ADP-ribosyltransferase from chicken heterophils. Eur J Biochem 204:305-311.
  4. Terashima M, Yamamori C and Shimoyama M (1995) ADP-ribosylation of Arg28 and Arg206 on the actin molecule by chicken arginine-specific ADP-ribosyltransferase. Eur J Biochem 231: 242-249.
  5. Terashima M, Shimoyama M and Tsuchiya M (1999) Introduction of NAD decreases fMLP-induced actin polymerization in chicken polymorphonuclear leukocytes - The role of intracellular ADP-ribosylation of actin for cytoskeletal organization. Biochem Mol Biol Int 47:615-620.
  6. Sheterline P and Sparrow JC (1994) Actin. Protein Profile 1:1-121.
  7. Kabsch W, Mannherz HG, Suck D, Pai EF and Holmes KC (1990) Atomic structure of the actin: DNase I complex. Nature 347:37-44. @
  8. Aktories K (1994) Clostridial ADP-ribosylating toxins: effects on ATP and GTP-binding proteins. Mol Cell Biochem 138:167-176.
  9. Holmes KC, Popp D, Gebhard W and Kabsch W (1990) Atomic model of the actin filament. Nature 347:44-49.
  10. Terashima M, Yamamori C, Tsuchiya M and Shimoyama M (1999) ADP-ribosylation of tubulin by chicken NAD-arginine ADP-ribosyltransferase suppresses microtubule formation. J Nutr Sci Vitaminol 45:393-400.

Discussion Board
Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS AND DISCUSSION] [FIGURES] [ACKNOWLEDGEMENTS] [REFERENCES] [Discussion Board]
ACKNOWLEDGEMENTS Previous: Testosterone modifies arylamidase activities in serum and different tissues of mice: an in vivo study. Previous: Intrinsic Membrane Properties and Synaptic Inputs Regulating The Firing Activity of the Dopamine Neurons. ABSTRACT
[Biochemistry]
Next: An extractable phosphatase inhibitor is present in the CSF of subarachnoid hemorrhage patients with vasospasm 		[Cell Biology & Cytology]
Next: Upregulation of phase II enzymes decreases the oxidative stress induced cell death in astrocytes.
Masaharu Terashima, Makoto Shimoyama, Mikako Tsuchiya
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Last update: 5/01/00