Poster | 6th Internet World Congress for Biomedical Sciences |
Alberto Pizarro Gallardo(1)
(1)Facultad de Medicina U.A.N. - Tepic. Mexico
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[Gastroenterology & Hepatology]![]() |
[Pathology]![]() |
The leiomyoblastoma or bizarre smooth-muscle tumor described by Stout(3) in the wall of the stomach may also be seen in the wall of the intestine, the mesentery. (4)
These neoplasm form solitary,well-defined, but not encapsulated, rounded or lobulated masses which, when small, tend to be localed intramurally; multiple tumors are rare. Growth may take place towards the lumen, resulting in a polypoid mass and is covered by an attenuated mucosa.
We recognize that the term "bizarre leimyoma" was formerly applied to stomach tumors with are now termed " leiomyoblastoma", it would seem to be an appropiate descriptive term for tumors under consideration. Evidence that these lesions may be overdiagnosed was leiomyosarcoma resulted in the reclassification of 31 as cellular leiomyoma and 17 as bizarre leiomyomas. The evidence that the tumors are, in fact, benign in convincing since none of the patient developed recurrence, metastasis, or died of disease within five years of treatment.
Microscopic features: the most important feature of leiomyoblastoma is the predominance of large, rounded or polygonal cells with the characteristic perinuclear clear zone in the cytoplams. The nuclei may be pleomorphic with prominent nucleoli.
Ultrastructural studies confirm the origin of these tumors from smooth muscle cells and indicate a clse relationship to small arteries and raise the possibility of an origin from perivascular myocites. The majority of these tumors are benign in character; recurrence, as with most connective tissue neoplams, is possible but metastasis is rare.(5)
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[Gastroenterology & Hepatology]![]() |
[Pathology]![]() |