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6th Internet World Congress for Biomedical Sciences

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Testosterone modifies arylamidase activities in serum and different tissues of mice: an in vivo study.

María Jesús García-López(1), María Jesús Ramírez-Expósito(2), José Manuel Martínez-Martos(3), María Dolores Mayas-Torres(4), Isabel Prieto-Gómez(5), Garbiñe Arechaga-Maza(6), Manuel Ramírez-Sánchez(7)
(1)(3)(4)(5)(6)(7)Unit of Physiology. University of Jaén - Jaén. Spain
(2)Unit of Physiology. University of Jaen - Jaén. Spain

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [DISCUSSION] [REFERENCES] [Discussion Board]
MATERIAL & METHODS Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity.
[Reproduction Sciences]
IMAGES
[Biochemistry]
Next: ADP-RIBOSYLATION OF FILAMENTOUS ACTIN INDUCES ITS DEPOLYMERIZATION - THE ROLE OF ADP-RIBOSYLATION IN CYTOSKELETAL REORGANIZATION
[Endocrinology]
Next: Evaluation of  body fat mass distribution by bioelectrical impedance in obese subjects
[Neuroscience]
Next: VASCULAR ISCHEMIC MYELOPATHY: CLINICAL - ELECTROPHYSIOLOGICAL MULTIMODAL INVESTIGATION
[Physiology]
Next: Endothelium Responses in Patients with Diabetic Peripheral Sensory
Neuropathy: A Laser Doppler Flowmetry Study.

RESULTS

The influence of orchiectomy and testosterone on Ala-, Arg-, and CysAP activities shows the following results:

In serum, AlaAP and CysAP did not change, but ArgAP activity decreased after orchiectomy. The injection of testosterone induced an increase in ArgAP activity. In frontal cortex, orchiectomy produced a significant decrease in soluble CysAP only. Testosterone induced a significant increase in soluble AlaAP. Higher soluble ArgAP and CysAP activities were observed after injection od doses E2 and E3. In hypothalamus, the soluble aminopeptidases analyzed, did not change after orchiectomy, but the injection of dode E2 of testosterone produced significant increases in soluble AlaAP, ArgAP and CysAP. However, membrane bound AlaAP, ArgAP and CysAP activities increase in orchiectomized group. Significant changes were observed in these AP activities after injection of testosterone. Soluble Ala, Arg and CysAP were increased in hypophysis in all the group analized. In adrenal glands, no changes were observed in soluble and membrane bound Ala, Arg and Cys AP activities after orchiectomy, but differences were observed between E1, E2 and E3 groups and control animals.


Discussion Board
Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [DISCUSSION] [REFERENCES] [Discussion Board]

MATERIAL & METHODS Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity. Previous: Influence of hormonal status on male mice aminopeptidase A activity.
[Reproduction Sciences]
IMAGES
[Biochemistry]
Next: ADP-RIBOSYLATION OF FILAMENTOUS ACTIN INDUCES ITS DEPOLYMERIZATION - THE ROLE OF ADP-RIBOSYLATION IN CYTOSKELETAL REORGANIZATION
[Endocrinology]
Next: Evaluation of  body fat mass distribution by bioelectrical impedance in obese subjects
[Neuroscience]
Next: VASCULAR ISCHEMIC MYELOPATHY: CLINICAL - ELECTROPHYSIOLOGICAL MULTIMODAL INVESTIGATION
[Physiology]
Next: Endothelium Responses in Patients with Diabetic Peripheral Sensory
Neuropathy: A Laser Doppler Flowmetry Study.
María Jesús García-López, María Jesús Ramírez-Expósito, José Manuel Martínez-Martos, María Dolores Mayas-Torres, Isabel Prieto-Gómez, Garbiñe Arechaga-Maza, Manuel Ramírez-Sánchez
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