María Jesús García-López⁽¹⁾, María Jesús Ramírez-Expósito⁽²⁾, José Manuel Martínez-Martos⁽³⁾, María Dolores Mayas-Torres⁽⁴⁾, Isabel Prieto-Gómez⁽⁵⁾, Garbiñe Arechaga-Maza⁽⁶⁾, Manuel Ramírez-Sánchez^{(7)
(1)(3)(4)(5)(6)(7)}Unit of Physiology. University of Jaén - Jaén. Spain
⁽²⁾Unit of Physiology. University of Jaen - Jaén. Spain

					[Reproduction Sciences]
	[Biochemistry]	[Endocrinology]	[Neuroscience]	[Physiology]

INTRODUCTION

Aminopeptidases (AP) are generally zinc-metalloenzymes which are thought to be involved in the metabolism of proteins an in the regulation of various peptide hormones (Sanderik et al., 1988). Previous results have suggested an influence of gonadal steroid on aminopeptidase activities (Gandarias et al., 1989; Martínez et al., 1997). In present the present work we analyzed the effects of orchiectomy and injection of different doses of testosterone on different AP activities. We measured alnyl aminopeptidase (E.C. 3.4.11.14) (AlaAP), arginyl aminopeptidase (EC 3.4.11.6) (ArgAP) and cystinyl aminopeptidase (EC 3.4.11.3) (CysAP) which have been reported to be active on several circulating and tissue peptides (McDonald and Barret, 1986).

Discussion Board

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[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [DISCUSSION] [REFERENCES] [Discussion Board]

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					[Reproduction Sciences]
	[Biochemistry]	[Endocrinology]	[Neuroscience]	[Physiology]

María Jesús García-López, María Jesús Ramírez-Expósito, José Manuel Martínez-Martos, María Dolores Mayas-Torres, Isabel Prieto-Gómez, Garbiñe Arechaga-Maza, Manuel Ramírez-Sánchez
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Last update: 15/01/00