María Jesús García-López⁽¹⁾, María Jesús Ramírez-Expósito⁽²⁾, José Manuel Martínez-Martos⁽³⁾, María Dolores Mayas-Torres⁽⁴⁾, Isabel Prieto-Gómez⁽⁵⁾, Garbiñe Arechaga-Maza⁽⁶⁾, Manuel Ramírez-Sánchez^{(7)
(1)(3)(4)(5)(6)(7)}Unit of Physiology. University of Jaén - Jaén. Spain
⁽²⁾Unit of Physiology. University of Jaen - Jaén. Spain

	[Biochemistry]	[Endocrinology]	[Neuroscience]	[Physiology]	[Reproduction Sciences]

INTRODUCTION

Aminopeptidases are generally zinc-metalloenzymes that have been used in clinical chemistry as serum markers for several diseases, and which also play a physiological role in the regulation of circulating biologically active peptides. Hormonal changes in the organism may be reflected in aminopeptidase activity. However, although their hydrolytic action on peptides or artificial substrates has been extensevely studied, the actual physiological role of these enzymes and their own mechanism of regulation are not well known.

Previous studies have suggested an influence of gonadal steroids on serum AP activities (Gandarias et al., 1989; Martínez et al., 1997). We studied the possible influence of orchiectomy and testosterone on aminopeptidase A activity (Aspartyl aminopeptidase and glutamyl aminopeptidase).

Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [DISCUSSION] [REFERENCES] [Discussion Board]

---

	[Biochemistry]	[Endocrinology]	[Neuroscience]	[Physiology]	[Reproduction Sciences]

María Jesús García-López, María Jesús Ramírez-Expósito, José Manuel Martínez-Martos, María Dolores Mayas-Torres, Isabel Prieto-Gómez, Garbiñe Arechaga-Maza, Manuel Ramírez-Sánchez
Copyright © 1999-2000. All rights reserved.

Last update: 15/01/00