Maria Rosa Sánchez⁽¹⁾, Manuel Samaniego^(2)
(1)Departamento de Bioquímica.. Hospital Universitario "San Cecilio". Granada - Granada. Spain
⁽²⁾Unidad Neonatal. Hospital Universitario "Virgen de las Nieves". - Granada. Spain

	[Biochemistry]

INTRODUCTION

Alkaline phosphatase (ALP) is a membrane-bound enzyme that is found in association with virtually all cells. ALP comprising four isoenzymes encoded by different structural genes: tissue nonspecific (bone, liver, renal), intestinal, placental, and germ cell (testis, thymus and lung). ALP in the lung has been localized to the plasma membrane and lamellar bodies of type II alveolar epithelial cells and its concentration in lung fluids has been used as a marker of damage of these cells.

Purpose of study: The aim of this study was to test the utility of alkaline phosphatase isoenzyme determinations, as injury markers of cellular membranes from bronchial ephiteliun, in patients diagnosed with bronchopulmonary pathology from different etiology, using serum and bronchoalveolar lavage fluid (BALF) samples.

Discussion Board

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[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [DISCUSSION] [CONCLUSIONS] [BIBLIOGRAPHY] [Discussion Board]

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	[Biochemistry]

Maria Rosa Sánchez, Manuel Samaniego
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Last update: 30/1/2000