María Jesús Ramírez-Expósito⁽¹⁾, José Manuel Martínez-Martos^(2)
(1)Unit of Physiology. University of Jaen - Jaén. Spain
⁽²⁾Unit of Physiology. University of Jaén - Jaén. Spain

	[Cell Biology & Cytology]	[Neuroscience]	[Physiology]

RESULTS

Figure 3 shows numerical cell density (mean±SEM) obtained in the different cortical layers of the frontal zone.

The study of the influence of ageing in the glial population of Fr cortex of the rat showed a significant increase (p<0.01) of total glia (TG) in cortical layer V of aged animals. However, the combination of ageing and contralateral lesions induced a significant increase (p<0.01) in all cortical layer except layer VI. In the same way, a significant increase of TG were observed in old and lesioned animals in reration with old animals. This increase was significat in cortical layer I, II-IV (p<0.01) and V (p<0.05).

The study of the different glial cells also showed a significant increase with aging in astrocyte population (A) in cortical layer V. However, aging and lesions together, induce a decrease (p<0.01) in the number of A in cortical layers II-IV and V in relation with old animals. In relation with young controls, old and lesioned animals increased (p<0.01) the A only in cortical layer I.

Ageing produced a significant decrease (p<0.05) in the number of microglia-oligodendrocytes in layer I. Rest of cortical layers presented no changes. The effects of ageing and lesioned induced significant increases (p<0.01) in all the cortical thickness.

Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCTION] [MATERIAL & METHODS] [RESULTS] [IMAGES] [DISCUSSION] [BIBLIOGRAPHY] [Discussion Board]

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	[Cell Biology & Cytology]	[Neuroscience]	[Physiology]

María Jesús Ramírez-Expósito, José Manuel Martínez-Martos
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Last update: 13/01/00