Poster
# 14
Poster |
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6th Internet World Congress for Biomedical Sciences |
leonardo bugatti(1), giorgio filosa(2), massimiliano nicolini(3), roberto verdolini(4)
(1)(2)dept of dermatology. "A. Murri" Hospital Jesi - Jesi. Italy
(3)(4)Dept of Dermatology. "A. Murri" Hospital Jesi - jesi . Italy
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[Dermatology] |
[Pathology] |
Linear focal elastosis (LFE) was repoted by Burket in 1989 (1). It is characterized by the presence of palpable asymptomatic yellow striae, with either a palpable consistency if localized on the back, or depressed on the arms, abdomen and breast. The age of onset ranges from 69 to 86 years with a male predilection, even though cases with childhood onset have beeen recently described.
Microscopic examination of the cutaneous lesions shows aggregated elastic fibers dissecting collagen bundles in the middle and lowe dermis. Electron microscopy confirms the presence of elastic fibers with a microfibrillar or an elastin component, mainly in the youngs and adult respectively (2). Histologic differential diagnosis is mainly with striae atroficae (). Clinical differential diagnosis includes: striae distensae, linear xantomas, pseudoxantoma elasticum, elastosis perforans serpiginosa, solar elastotic bands(3). Pathogenesis is unknown. While some Authors believe that LFE is a peculiar variant of strieae distensae (4), others argue that LFE must be considered an hamartomatous/nevoid degenerative or regenerative process of elastic fibers as a response to mechanical stimuli such as physical trauma or solar radiations (5,6).
In summary, we think that the latter hypothesis can well explain the dorsal localization of the lesions in response to abnormal mechanical stimula in predisposed subjects.
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[Dermatology] |
[Pathology] |
