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# 11

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6th Internet World Congress for Biomedical Sciences

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Morphometric study of the coronary atherosclerosis in autopsy of diabetic, hypertensive and diabetics and hipertensive subjects.
(Análisis morfométrico de la aterosclerosis de las arterias coronarias en fallecidos diabéticos, hipertensos y diabéticos e hipertensos)

Roberto Cuan Ravinal(1)
(1)Departamento de Patologia. USP-Ribeirão Preto. Facultade de Medicina. - Ribeirão Preto. Brazil

Discussion Board Contact address: Roberto Cuan Ravinal
Departamento de Patologia USP-Ribeirão Preto. Facultade de Medicina.
Edificio Ircury, Rua Duque de Caxias 437 Apartamento 52; 5 Andar; Centro. Ribeirão Preto. CEP: 14015020. São Paulo. Brasil. Ribeirão Preto
São Paulo CEP: 14015020 Brazil
cuan@rpa.fmrp.usp.br
[ABSTRACT] [INTRODUCCIÓN] [OBJETIVOS] [MATERIAL Y MÉTODOS] [RESULTADOS Y DISCUSIÓN] [CONCLUSIONES] [BIBLIOGRAFÍA] [Discussion Board]
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[Cardiolovascular Diseases]
Next: Contraindications to thiazides and beta blockers in hypertense patients treated with nifedipine in five Cuban municipalities.
[Nutrition & Diabetics]
Next: Endothelium Responses in Patients with Diabetic Peripheral Sensory
Neuropathy: A Laser Doppler Flowmetry Study.
[Pathology]
Next: Does lignin affect intestinal morphometry?

ABSTRACT

An atherometric system was used to study coronary atherosclerotic lesions of the a sample of 53 autopsy subjects, divided into the three groups: a) hypertensive, 29 subjects; b) diabetics, 12 subjects; c) hypertensive and diabetic, 12 subjects. Classical pathomorphological procedures and atherometric system suitable to characterize the atherosclerotic lesions, was used searching for differences between the level of atherosclerosis into these three groups. Raw data processing was full automated and some univariate and multivariate statistical procedures were performed using commercial statistical packages. The most remarkable findings were the following: diabetes and hypertension have both strong impact which the atherosclerotic process. The impact of diabetes and hypertension seems to be stronger and are particularly expressed by the severe plaques in the left circumflex artery and fibrous plaques in the right coronary artery. A high significance of all variables of this system: total atherosclerosis, obstruction and benignity indices were found between the groups studied.


Se realizó un estudio observacional, longitudinal y descriptivo en una muestra de 53 fallecidos, siendo 29 hipertensos, 12 diabéticos y 12 diabéticos e hipertensos; para determinar la distribución de la lesión aterosclerótica, analizar la patomorfología y morfometría del grado de afectación de la lesión aterosclerótica y comparar estadísticamente el comportamiento de la aterosclerosis de las arterias coronarias derecha, descendente anterior y circunfleja izquierda entre los grupos de estudio, mediante el Sistema Aterométrico. Se halló la estadística descriptiva e inferencial con test t de Student para comparar los valores de la media de las variables entre dichos grupos. Los diabéticos e hipertensos presentaron un proceso aterosclerótico más severo y predominó la placa grave en la arteria circunfleja izquierda y la placa fibrosa en las arterias coronarias derecha y descendente anterior. Resultaron significativas las variables arteriales correspondientes al total de aterosclerosis, índice de obstrucción e índice de benignidad entre los diabéticos y diabéticos e hipertensos en los tres segmentos coronarios.


Keywords: Morphometry - Atherosclerosis - Coronary Artery -

Discussion Board
Discussion Board

Any Comment to this presentation?

[ABSTRACT] [INTRODUCCIÓN] [OBJETIVOS] [MATERIAL Y MÉTODOS] [RESULTADOS Y DISCUSIÓN] [CONCLUSIONES] [BIBLIOGRAFÍA] [Discussion Board]

Main Page Previous: Cholesterol Granuloma (Cholesteroloma) Of The Mammary Gland INTRODUCCIÓN
[Cardiolovascular Diseases]
Next: Contraindications to thiazides and beta blockers in hypertense patients treated with nifedipine in five Cuban municipalities.
[Nutrition & Diabetics]
Next: Endothelium Responses in Patients with Diabetic Peripheral Sensory
Neuropathy: A Laser Doppler Flowmetry Study.
[Pathology]
Next: Does lignin affect intestinal morphometry?
Roberto Cuan Ravinal
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