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      Nº 043

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SIGNIFICADO PRONOSTICO DE LA EXPRESION DE PROTEINAS RELACIONADAS
CON LA APOPTOSIS BCL-2 Y BAX EN CARCINOMA DUCTAL INFILTRANTE DE MAMA
CON GANGLIOS LINFATICOS NEGATIVOS

MF Fresno, MJ Pérez del Rio, B. Madrigal, M Veiga, JM Diaz Iglesias(*) y A Herrero

Comentarios

[TITULO] [INTRODUCCIÓN] [MATERIAL Y MÉTODOS] [RESULTADOS] [ICONOGRAFÍA] [DISCUSIÓN] [BIBLIOGRAFÍA]

DISCUSIÓN

BIBLIOGRAFÍA


BIBLIOGRAFÍA

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14.- Lipponen P, Pietilainen T, Kosma VM, Aaltomas S, Eskelinen M, Syrjanen K. Apoptosis suppresing protein bcl-2 is expressed in well-differentiated breast carcinomas with favourable prognosis. J Pathol 1995; 177: 49-55.

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16.- Bhargava V, Kell DL, Van de Rijn M, Warnke RA. Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity. Am J Pathol 1994; 145: 535-540.

17.- Silvestrini R, Benini E, Veneroni S, Daidone MG, Tomasic G, Squiccirini P, Salvadori B. p53 and Bcl-2 expression correlates with clinical outcome in a series on node-positive breast cancer patients. J Cli Oncol 1996; 14: 1604-1610.

18.- R, Veneroni S, Daidone MG et al. : The bcl-2 protein: a prognostic indicator strongly related to p53 protein in lymph node negative negative breast cancer patients. J Natl Cancer Inst 1994, 86:499-504

19.- Gorczyca W, Markiewski M, Kram A, Tuzi T, Domagala W. Immunohistochemical analysis of bcl- 2 and p53 expression in breast carcinomas: their correlation with Ki-67 growth fraction. Virchows Arch 1995; 426: 229-233.

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22.-Hellemans P, Van Dam PA, Weyler J, Van Oosterom AT, Buytaert P, Van Marck E. Prognostic value of Bcl-2 expression in invasive breast cancer. Br J Cancer 1995;72:354-360

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25.-Kapranos N, Karaiosifidi H, Valavanis C, Kouri E, Vasilaros S .Prognostic significance of apoptosis related proteins Bcl-2 and Bax in node-negative breast cancer patients. Anticancer Res, 1997; 17:4A, 2499-505

26.- Binder C, Marx D, Binder L, Schauer A, Hiddemann W. Expression of Bax in relation to Bcl-2 and other predictive parameters in breast cancer. Ann Oncol, 1996 Feb, 7:2, 129-33

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28.-Kapucuoglu N, Losi L, Eusebi V . Immunohistochemical localization of Bcl-2 and Bax proteins in in situ and invasive duct breast carcinomas. Virchows Arch, 1997 ; 430:17-22

29.- Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius VM, Niskanen E, Nordling S, Reed JC. Reduced expression of the proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and sorther survival in women with metastatic breast adenocarcinoma. Cancer Res 1995; 55:4471-4478.

[TITULO] [INTRODUCCIÓN] [MATERIAL Y MÉTODOS] [RESULTADOS] [ICONOGRAFÍA] [DISCUSIÓN] [BIBLIOGRAFÍA]

DISCUSIÓN

BIBLIOGRAFÍA


MF Fresno, MJ Pérez del Rio, B. Madrigal, M Veiga, JM Diaz Iglesias(*) y A Herrero
Copyright © 1998. Reservados todos los derechos.