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6th Internet World Congress for Biomedical Sciences

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Invited Symposium: Pathology and Genetics of Nervous System Tumors (4 Presentations in this Symposium)

p53 inactivation through cytoplasmic expression in neuroblastoma

Xing Fan(1), Lourdes Gómez(2), Angel Pestaña(3), Luis Santamaría(4), Manuel Nistal(5), Javier Saez Castresana(6)
(1)Department of Genetics. University of Navarre - Pamplona. Spain
(2)Department of Genetics. University of Navarra - Pamplona . Spain
(3)Instituto de Investigaciones Biomedicas, CSIC - Madrid. Spain
(4)Department of Morphology (Histology) . Universidad Autonoma de Madrid (UAM) - Madrid. Spain
(5)Department of Morphology (Histology). Universidad Autónoma de Madrid (UAM) - Madrid . Spain
(6)Departamento de Genetica. Universidad de Navarra - Pamplona. Spain

[ABSTRACT] [FIGURES] [Discussion Board]
ABSTRACT Previous: From Postganglionic Sympathetic Nervous System To Neuroblastoma ABSTRACT
Next: In vivo studies on the effect of autocrine Transforming Growth Factor-<font face="symbol">a</font> in glioma cells

FIGURES

fig. 1
Fig. 1: Indifferentiated Neuroblastoma. Positive immunostaining for p53 (3+): general staining in the cellular nuclei (X40).

 

fig. 2
Figuras 2: Ganglioneuroblastomas. Positive immunostaining for p53. p53 citoplasmic expression is detected at the ganglionic neuron cells. Counter stained with hematoxylin (X40).

 

fig. 3
Figuras 3: Ganglioneuroblastomas. Positive immunostaining for p53. p53 citoplasmic expression is detected at the ganglionic neuron cells. Counter stained with hematoxylin (X40).

 

fig. 4
Fig. 4: Indifferentiated Neuroblastoma. Negative immunostaining for p53. Counter stained with methyl green (X40).

 

fig. 5
Fig. 5: Indifferentiated Neuroblastoma. Positive immunostaining for PCNA (3+): general staining in the cellular nuclei (X40).

 

fig. 6
Fig. 6: Indifferentiated Neuroblastoma. Positive immunostaining for PCNA (1+ ó 2+): a small number of nuclei appear stained. The greatest part of the section corresponds to negative PCNA. Counter stained with methyl green (X40).

 


Discussion Board
Discussion Board

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[ABSTRACT] [FIGURES] [Discussion Board]

ABSTRACT Previous: From Postganglionic Sympathetic Nervous System To Neuroblastoma ABSTRACT
Next: In vivo studies on the effect of autocrine Transforming Growth Factor-<font face="symbol">a</font> in glioma cells
Xing Fan, Lourdes Gómez, Angel Pestaña, Luis Santamaría, Manuel Nistal, Javier Saez Castresana
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