HEPATITIS DE CÉLULAS GIGANTES SINCITIALES: ESTUDIO HISTOLÓGICO E INMUNOHISTOQUÍMICO DE UN CASO.

SYNCITIAL GIANT-CELL HEPATITIS: HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY OF ONE CASE.

S. Ambrosi, M.D., P. Di Zitti, M, M., A. Baiocchini, M. D.

[TITULO] [INTRODUCCIÓN] [CASO CLÍNICO] [RESULTADOS] [ICONOGRAFÍA] [DISCUSIÓN] [BIBLIOGRAFÍA]

INTRODUCCIÓN

“Post-infantile giant cell hepatitis” or “Adult giant cell hepatitis” (AGCH) is a variety of hepatitis characterized by a diffuse multinucleated giant cell transformation of hepatocytes (GTH) that generally combines with histological pictures of a non otherwise specified chronic hepatitis , i.e. inflammation, necrosis and fibrosis ( 2, 4, 6, 7 ). The disease may have either an acute and a chronic clinical presentation. Spontaneous recovery occurs in almost 25% of patients and mortality varies according to etiology. It is assumed that at least a third of patient die following acute disease or from complication of chronicity. In the remainder of cases there’s an evolution toward cirrhosis and progressive liver failure ( 1 ). We report a case of ACGH occurring in a young adult woman and describe some immunohistochemical properties of giant cells.

[TITULO] [INTRODUCCIÓN] [CASO CLÍNICO] [RESULTADOS] [ICONOGRAFÍA] [DISCUSIÓN] [BIBLIOGRAFÍA]

S. Ambrosi, M.D., P. Di Zitti, M, M., A. Baiocchini, M. D.
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