Comunicación Nº: 053  

Determinación en ratas de la LD50 de extractos de frutos de Melia azedarach L. Comportamiento y sintomatología de las ratas. Estudio histopatológico de los órganos.

María Cecilia Carpinella, M.M. Oviedo, Susana Fulginiti, S.M. Palacios.

[Título] [Introducción] [Material y Métodos] [Resultados] [Iconografía] [Discusión]




1-Lee, S.M., Klocke, J.A. and Balandrin, M.F. (1987) The structure of 1- cinnamoylmelianolone, a new insecticidal tetranortriterpenoid, from Melia azedarach L. (Meliaceae). Tetrahedron Lett. 28, 3543-3546.

2-Jacobson M., (1989) Botanical Pesticides: Past, Present and Future. In: Insecticides of Plant Origin, pp. 1-10 ( Arnason, J.T., Philogene, B.J.R. and Moranal, P. Eds.). American Chemical Society Symposium Series: .

3-Palacios, S.M., Valladares, G., and Ferreyra, D. (1993) Preliminary results in the searching of an insecticide from Melia azedarach extracts. In: Practice Oriented Results on Use and Production of Neem - Ingredients and Pheromones, pp. 99-105 (Kleeberg, H., Ed.). Giesen: Druck & Graphic.

4-Lee, S.M., Klocke, J.A., Barnby, M.A., Yamasaki, R.B. and Balandrin, M.F. (1991) Insecticidal constituents of Azadiachta indica and Melia azedarach (Meliacea). In: Natural Occuring Pest Bioregulators, pp. 293-304 (Hedin, P.A., Ed.). Washignton DC: American Chemical Society.

5-Kraus, W., Bokel, M., Klenk, A. and Pöhnl, H. (1985) The structure of Azadirachtin and 22,23- Dihydro-23ß-Methoxyazadirachtin. Tetrahedron Lett. 26, 6435-6438.

6-Wachsman, M.B., Dasmonte, E.B., Coto, C.E. and de Torres, R.A. (1987) Antiviral effects of Melia azedarach L. leaves extracts on Sindbis virus-infected cells. Antiviral Research 8, 1-12.

7-Coulombié, F.C., Andrei, G.M., Laguens, R.P., de Torres, R.A. and Coto, C.E. (1992) Partially purified leaf extracts of Melia azedarach L. inhibit Tacaribe Virus growth in neonatal mice. Phytotherapy Researh 6, 15-19.

8-Morrison, F.R. and Grant, R. (1932) Contribution to the chemistry of the fruit obtained from the White Cedar tree (Melia azedarach L. var. australasica C.D.C.: Melia australasica A.Juss growing in New South Wales, with notes on its reputed toxicity. J. Proc. Roy. Soc. N.S.W. 65, 153- 177.

9-Steys, D.G. and Rindl, M. (1929)Preliminary report on the toxicity of the fruit of Melia azedarach (Syringa Berries). Transactions of the Royal Society of South Africa 17, 295-307.

10-Oelrichs, P.B., Hill, M.W., Vallely, P.J., MacLeod, J.K. and Molinski, T.F. (1983) Toxic Tetranortriterpenes of the fruit of Melia azedarach. Phytochemistry 22, 531- 534.



María Cecilia Carpinella.
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