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Alcohol enhances the sedative effect of zolpidem, joint use is not recommended. Drugs that act depressingly on the central nervous system (neuroleptics, barbiturates, other sleeping pills, anxiolytics / sedatives, antidepressants with sedative action, narcotic analgesics, antitussive central action), antiepileptic drugs, general anesthetics, antihistamines with sedative effect, antihypertensive central action; baclofen; thalidomide; pizotifen - when combined, there is an intensification of the oppressive effect on the central nervous system and the risk of respiratory depression increases; buprenorphine - risk of respiratory depression; ketoconazole (a powerful inhibitor of CYP3A4) reduces the clearance of zolpidem, in connection with which it is possible to increase its sedative effect; itraconazole (inhibitor CYP3A4) - a slight, clinically insignificant change in the pharmacokinetics and pharmacodynamics of zolpidem. Rifampicin (inducer CYP3A4) accelerates metabolism, reduces the concentration and effectiveness of zolpidem.


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Doctors prescribe Ambien for insomnia. The drug helps to improve the quality of sleep, reduce period of falling asleep and a number of the night awakenings. As a rule, insomnia is associated with very stressful period in life. This is excessive fatigue at work, or stress, or other issues. To maintain a vital energy, people prefer taking a stimulant. Caffeine is one of the most popular. Coffee is not the only source of caffeine. Tea, energy drinks and other products also contain this ingredient. Therefore, consuming more caffeine products, a person is full of energy within a day. At home, many people take a pill of Ambien and hope for a good healthy sleep. And just some of them think about a compatibility of Ambien with coffee or other products containing caffeine.

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Doctors prescribe Ambien for insomnia. The drug helps to improve the quality of sleep, reduce period of falling asleep and a number of the night awakenings. As a rule, insomnia is associated with very stressful period in life. This is excessive fatigue at work, or stress, or other issues. To maintain a vital energy, people prefer taking a stimulant. Caffeine is one of the most popular. Coffee is not the only source of caffeine. Tea, energy drinks and other products also contain this ingredient. Therefore, consuming more caffeine products, a person is full of energy within a day. At home, many people take a pill of Ambien and hope for a good healthy sleep. And just some of them think about a compatibility of Ambien with coffee or other products containing caffeine.

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Dizziness may occur. If this effect persists or worsens, tell your doctor or pharmacist promptly. This medication may make you sleepy during the day. Tell your doctor if you have daytime drowsiness. Your dose may need to be adjusted. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: memory loss, mental/mood/behavior changes (such as new/worsening depression, abnormal thoughts, thoughts of suicide, hallucinations, confusion, agitation, aggressive behavior, anxiety). Rarely, after taking this drug, people have gotten out of bed and driven vehicles while not fully awake ("sleep-driving"). People have also sleepwalked, prepared/eaten food, made phone calls, or had sex while not fully awake.

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