Congreso Virtual sobre Anatomía Patológica

Virtual Slide Congress. Case # 13

Francisco Martín Dávila*
* Hospital General de Ciudad Real ESPAÑA

Title

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76 years old male with a neoplasia in his left kidney suggestive of malignancy
(Varón de 76 años de edad con una neoplasia en riñón izquierdo).

 

Case Report    

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Summary of the clinical history: 76 years old male with a neoplasia in his left kidney suggestive of malignancy. It was treated with radical nephrectomy.
 
Gross study: A radical nephrectomy specimen of 12x8x7 cm. and 296 gr. of weight was received. After an easily decapsulation process the kidney showed a neoplasia with irregular and ill-defined borders of 9x8 cm of maximum diameters, approximately. It had a white cut surface with mixed areas of a yellowish coloration. The tumour occupied all the thickness of the renal parenchyma and was infiltrating in some points the perirenal fat and the adipose tissue of the sinus. The rest of the kidney was normal in appearance with some small cysts near the surface and a relative good delimitation between cortex and medulla.

Resumen de historia clínica: Varón de 76 años de edad con una neoplasia en riñón izquierdo. Se practica nefrectomía radical.
 
Descripción macroscópica: Se recibe pieza de nefrectomía radical de 12x8x7 cm y de 296 gr. de peso. Se decapsula con cierta dificultad pero totalmente y muestra, al corte, un área tumoral de límites mal definidos, que mide, aproximadamente, 9x8 cm. Es de coloración blanquecina con áreas amarillentas en su interior afectando a la grasa del sinus y ocupando todo el espesor del riñón, contactando con grasa perirrenal. El resto del parénquima renal muestra una relativamente buena delimitación cortico-medular con pequeñas áreas cicatriciales. Los vasos del hilio no muestran alteraciones.

 

DIAGNOSIS    

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COLLECTING DUCT CARCINOMA (BELLINOMA)
(CARCINOMA RENAL DE LOS CONDUCTOS COLECTORES)

 

Pathology    

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Microscopic description: The renal neoplasia was epithelial in appearance and composed of nests and papillary structures filled and lined, respectively, by cells with wide eosinophilic cytoplasms and vesiculous nucleus. There were extensive necrotic areas. At the inner part of the tumor the neoplastic cells replaced partially the urothelial epithelium that normally covers the pelvic calyx and also the cells of the distal portion of the collecting ducts. Immunohistochemically, tumoral cells were strongly positive for CK-19.
 
Diagnostic: HIGH GRADE COLLECTING DUCT CARCINOMA (HIGH GRADE BELLINOMA)

Descripción microscópica: Se observa una neoplasia epitelial que se dispone formando nidos y estructuras papilares y tubulares dilatadas, revestidos por una sola capa de células de citoplasma amplio, eosinófilo y núcleo de aspecto vesiculosos. Existen frecuentes áreas de necrosis. La neoplasia se extiende por el recubrimiento urotelial de la pelvis y por la desembocadura de los conductos colectores. La célula tumoral es fuertemente positiva para CK-19.
 
Diagnóstico: CARCINOMA DE LOS CONDUCTOS COLECTORES DEL RIÑÓN (BELLINOMA) DE "ALTO GRADO".

 

Discusión    

Conclusiones    

 

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